Sox2 genecards
WebThe interactive pathways and diagrams have been created by CST scientists and outside experts to provide concise overviews of selected signaling pathways and cellular mechanisms. Protein nodes in each interactive diagram are linked to specific antibody product information, as well as protein-specific listings in the PhosphoSitePlus ® … Web10. jan 2024 · GeneCards Summary for LOC108281177 Gene LOC108281177 (SOX2 5' Regulatory Region) is a Functional Element gene. Additional gene information for …
Sox2 genecards
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WebSOX2OT lncRNA is known to regulate chromatin architecture [60] and is located 12 kb upstream of SOX2. The expression of SOX2OT is very high in TMZ-resistant cells and it was found that knockdown of SOX2OT resulted in enhanced TMZ sensitivity in TMZ-resistant GBM cancer cells (Fig. 4).Besides, the increased SOX2OT expression levels also induce … http://www.laizee.com/en/news/view/id-65.html
Web11. júl 2024 · SOX2 is highly expressed in LSCC tissues and associated with poor prognosis of LSCC. LSCC-related genes were retrieved from GeneCards (the top 300), DisGeNET … WebR-HSA-2892245 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation; R-HSA-2892247 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; R …
Web2. apr 2015 · Thus, Sox2 interferes with the tumour-suppressive Hippo pathway to maintain CSCs in osteosarcomas. This Sox2-Hippo axis is conserved in other Sox2-dependent … WebSRY盒-2（SRY：性別決定區，Sex Determining Region Y），又稱「Sox2」（人的Sox2應寫爲SOX2），是一種對未分化的胚胎幹細胞（ESC）、神經幹細胞等再生能力以及多能性維持至關重要轉錄因子[5]。 對Sox2的研究對幹細胞生物學、再生醫學的發展有重要意義[6]。 Sox2隸屬於SOX轉錄因子家族。 Sox轉錄因子家族在哺乳動物的發育過程中扮演重要角色 …
Web19. aug 2013 · SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network. SOX2 was reported to promote …
Web10. apr 2024 · SOX2 is necessary for the normal development and function of the hypothalamo-pituitary and reproductive axes in both humans and mice. These data suggest that SOX2 plays an important role in regulation of pepsinogen A, and ectopic expression of SOX2 may be associated with abnormal differentiation of colorectal cancer cells. ducts unlimited cleaning servicesWebSOX2 represents a High Mobility Group domain containing transcription factor that is essential for normal development in vertebrates. Mutations in SOX2 are known to result in … duct supports and hangersWeb9. feb 2010 · Methodology/principal findings: We assessed the expression of SOX2, an embryonic stem cell transcriptional factor that also plays important roles in the proliferation of basal tracheal cells and whose expression is restricted to the main and central airways and bronchioles of the developing and adult mouse lung, in NSCLC by various … common woodrushWebThis gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000325404.3 Gencode Gene: ENSG00000181449.4 Transcript (Including UTRs) Position: hg38 chr3:181,711,925-181,714,436 Size: 2,512 Total Exon Count: 1 Strand: + Coding Region commonwood pubWebGST pull-down and coimmunoprecipitation assays showed that OTX2 and SOX2 physically interacted, and this interaction was affected by missense mutations located in helices 2 and 3 of the SOX2 HMG domain (R74P, 184429.0008; L97P, 184429.0004, respectively), resulting in reduced induction of transcription via RAX CNS1. common woodshrikeWebIn other projects. Eomesodermin - Eomesodermin EOMES; Azonosítók; Álnevek: EOMES, TBR2, Eomesodermin: Külső azonosítók commonwood sarasotaWeb21. mar 2024 · GeneCards Summary for SOX10 Gene SOX10 (SRY-Box Transcription Factor 10) is a Protein Coding gene. Diseases associated with SOX10 include Peripheral … duct spray foam