Webb11 apr. 2024 · Since amiodarone is an inhibitor of the cytochrome P450-3A4 system … Webb11 dec. 2014 · Simvastatin and atorvastatin: interactions Many important interactions …
Simvastatin–Amiodarone Interaction Resulting in Rhabdomyolysis …
Webb1 mars 2011 · Amiodarone has been found to significantly increase the bioavailability of simvastatin, while not affecting pravastatin (Becquemont et al. 2007). Cases of rhabdomyolysis have been reported on... Webb11 dec. 2014 · The changes include contraindications to concomitant use with certain medicines and maximum dose recommendations when simvastatin is taken with a number of other medicines, as these... red fury from antboy
Adverse effects of interactions between antipsychotics
Webb1 apr. 2006 · Simvastatin is metabolized primarily by CYP3A4, and amiodarone is a … Webb15 mars 2016 · Simvastatin – amiodarone interaction : Increased risk of rhabdomyolysis . How the interaction occurs: Amiodarone may slow down how quickly liver metabolize cholesterol medicine ( simvastatin). but is related to the fact that amiodarone inhibits the cytochrome P450 3A4 (CYP3A4) enzyme. This is the same enzyme that metabolizes … WebbAn interaction of simvastatin with amiodarone has been described.. A 63-year-old white man with insulin-dependent diabetes and recent coronary artery bypass surgery developed diffuse muscle pain with generalized muscular weakness after taking amiodarone 1 g/day for 10 days then 200 mg/day plus simvastatin 40 mg/day [71].He had a significant … red fury dc